pentobarbital will reduce the extent or impact of ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Powerful CYP3A4 inducers may possibly decrease partiaprevir and ritonavir degrees, and so lowered efficacy of Viekira Pak
pentobarbital improves toxicity of ifosfamide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. CYP3A4 inducers might increase the metabolism of ifosfamide to its Energetic alkylating metabolites.
pentobarbital will minimize the extent or result of lumacaftor/ivacaftor by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
pentobarbital will minimize the extent or outcome of tamoxifen by influencing hepatic enzyme CYP2C9/ten metabolism. Use Caution/Check.
pentobarbital will decrease the extent or result of lefamulin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. Avoid coadministration of lefamulin with robust or reasonable CYP3A inducers Except the benefit outweighs hazards. Watch for lessened efficacy.
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pentobarbital will decrease the level or influence of cevimeline by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unidentified.
pentobarbital will decrease the extent or outcome of fosaprepitant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will minimize the extent or impact of pimavanserin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. Steer clear of coadministration if at all possible. Observe for minimized pimavanserin efficacy. A rise in pimavanserin dosage can be necessary.
pentobarbital will decrease the extent or impact of eltrombopag by affecting hepatic enzyme CYP2C9/ten metabolism. Use Caution/Monitor.
Sluggish IV injection is essential, and clients ought to be diligently observed through administration. This demands that blood pressure level, respiration, and cardiac functionality be preserved, essential indicators be recorded, and devices for resuscitation and synthetic air flow be obtainable. The rate of IV injection shouldn't exceed 50 mg/min for pentobarbital sodium.
pentobarbital will minimize the extent or effect of eplerenone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Not known.
Estradiol, estrone, website progesterone and various steroidal hormones: Pretreatment with or concurrent administration of phenobarbital may decrease the outcome of estradiol by rising its metabolism.
pentobarbital will lessen the extent or influence of imatinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Mysterious.